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2 results for “chalcones”

SYNTHESIS, CHARACTERIZATION, ENZYMATIC ACTIVITY OF SOME PYRAZOLINE DERIVATIVES, AZO DYES, AND CHALCONES DERIVED FROM ETHYL 4-(TRIFLUOROMETHYL)BENZOATE

Sh.H. Abdullah1, A.B. Saber1, K.A. Al-Badrany1, J.N. Saleh2, M.J. Saleh2

Abstract: This study reports the use of 4-(trifluoromethyl)benzoate as a key synthone for preparing a series of heterocyclic derivatives. Reaction completion was verified by thin-layer chromatography (TLC), and the products were characterized by physical properties (color, yield, and melting point), Fourier-transform infrared spectroscopy (FT-IR), and…

Keywords: chalcone, azo dyes, pyrazine, acid hydrazide, enzymatic activity

DOI: 10.65382/2221-8688-2026-3-346-361

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PREPARATION AND CHARACTERIZATION OF INDOLE-3-CARBALDEHYDE-DERIVED PYRAZOLINE DERIVATIVES AND EVALUATION OF BIOLOGICAL EFFICACY

J.H. Saleh, M.G. Abdulkarim

Abstract: The research involved the preparation of a series of chalcones [I1-I5] by the reaction of indole-3-carbaldehyde with acetophenone substituents in a basic medium. The prepared chalcones were then reacted with aqueous hydrazine in the presence of glacial acetic acid as a catalyst to form…

Keywords: heterocyclic; chalcones; pyrazoline; biological activity

DOI: 10.65382/2221-8688-2026-4-599-569

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