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SPECTROPHOTOMETRIC DETERMINATION OF DOXORUBICIN HYDROCHLORIDE USING CHARGE TRANSFER COMPLEXES REACTION

Tabarak A. Abdulwahd, Omar A. Sheej Ahmad

A new, simple, sensitive, and rapid spectrophotometric method has been developed for the determination of doxorubicin hydrochloride (DOX) via charge-transfer complex formation with o-chloranil in its pure form and pharmaceutical preparations (injection). The method is based on the formation of a stable 2:1 (Reagent: Drug)…

Keywords: Spectrophotometric analysis, o-chloranil, doxorubicin, charge-transfer complex formation

DOI: 10.65382/2221-8688-2026-4-660-669

RESEARCH INTO HYDROGEL SWELLING CAPACITY ON THE BASIS OF POLYACRYLIC ACID AND IMMOBILIZATION OF DOXORUBICIN THEREUPON

S.M.Mammadova, Sh.Z.Tapdigov, S.F.Humbatova, S.F.Safaraliyeva, M.Kh.Hasanova, N.A.Zeynalov

RESEARCH INTO SORBTION PROPERTIES AND STRUCTURES OF POLYMER HYDROGEL IMMOBILIZED BY DOXORUBICIN

S.M. Mammadova, Sh.Z. Tapdigov, S.F. Humbatova, N.A. Zeynalov, A.R. Guliyeva, E.M. Gasımov

DESİGNİNG POLY-N-VİNYLPYRROLİDONE BASED HYDROGEL AND APPLİED HİGUCHİ, KORSMEYER-PEPPAS, HİXSON-CROWELL KİNETİC MODELS FOR CONTROLLED RELEASE OF DOXORUBİCİN

Sh. Z. Tapdiqov

DOI: 10.32737/2221-8688-2020-2-207-213

SYNTHESIS, ANTICANCER ACTIVITY, MOLECULAR DOCKING STUDY, OF 4,4DICHLORO-1,3-OXAZILIDINE-5-ONE DERIVED FROM ISONIAZID

Khalaf A. Jasim^1*, Sheerin Farouq Shaker¹, Dardaa Aziz Ibrahim¹, Zaid A. Dawood², Sarab Dalaf Khalaf³, Adil Hussein Dalaf¹, Andre J. Gesquiere^{4, 5}

Abstract: Breast cancer is considered one of the increasingly serious problems affecting women recently, so many parties are seeking to find effective solutions that reduce its risks. Therefore, the research paper aimed to synthesize hydrazide–hydrazones of isoniazid (T1–T5), which underwent reaction with trichloroacetic acid (TCA),…

Keywords: isoniazid, 4,4-dichloro-1,3-oxazilidine-5-one, anticancer, molecular docking.

DOI: 10.65382/2221-8688-2026-2-312-329