Abstract
In this work, seven new Schiff bases were obtained in two ways. In method (A), an equimolecular aqueous solution of glucose and an alcoholic solution of amine were refluxed for three hours, and in method (B), a deep eutectic solvent (Reline), prepared from one mole of choline chloride and two moles of urea,was used as catalyst. The reaction yield percentage in the traditional method (A) was found to be 60-79%, and in the catalytic method (Method B) using a deep eutectic solvent (Reline) yield percentage was 88-95%. The deep eutectic solvent catalytic system (Reline) is an environmentally friendly solution with the triple benefit of increased percentage yield, elimination of solvent, and faster reaction time by reducing reflux time by up to three times (i.e., just one hour).