Abstract
The one-step interaction of substituted ylidenecyanoacetamides (or ylidenema- lononitriles), malononitrile and 1,3-diaminopropane was carried out in methanol environment at room temperature and it established the formation of new substituted dihydropyridopyrimidine deri- vatives. It also revealed that under the same conditions through the use of one-step three- component reaction of pyridylidenecyanoacetamide (or pyridylidenemalononitrile), 2-chloro-5- nitrobenzylidenecyanoacetamide (or 2-chloro-5-nitrobenzylidenemalononitrile), 2,6- dichlorobenzylidenecyanoacetamide (or 2,6-dichlorobenzylidenemalononitrile), malononitrile and 1,3-diaminopropane there formed substituted derivatives not of dihydropyridopyrimidine but tetrahydropyridopyrimidine. Structures of all synthesized compounds were verified by NMR and X-Ray spectroscopy.