Abstract
The article explores the synthesis of 2-piperidinomethyl-4-methylcycloalkylphenols as a result of aminomethylation reactions of p-[1(3)-methylcycloalkyl]phenols obtained by catalytic cycloalkylation reactions of phenol and 1-methylcyclopentene, 1- and 3-methylcyclohexenes with piperidine. Aminomethylation reactions were carried out through the interaction of p-cycloalkylphenols with 30% of formaldehyde and piperidine in the presence of a solvent. The reaction was realized at 30C for 2 hours. Following results of the studies, it revealed that yields of the obtained target products amounted to 68.8- 75.6% on p-(methylcycloalkyl). Chemical structures of 2-piperidinomethyl-4-methylcycloalkylphenols were confirmed by IR, 1H and 13C NMR spectroscopies, and physicochemical properties determined as well.